Luc Jasmin, MD, PhD


Curriculum Vitae (abbreviated)


PART I: General Information

Education:
1976 Minor (Chemistry) Univ. Montréal, Canada
1981 M.D. (Medicine) Univ. Montréal, Canada
1987 Ph.D (Neuroanatomy) Univ. Montréal, CanadaPostdoctoral Training:
1981-1982 Internship Surgery Notre-Dame Hospital, Univ. Montréal, Canada
1982-1990 Resident Neurosurgery Notre-Dame Hospital, Univ. Montréal, Canada
1990-1993 Research Anatomy University of California, San Francisco
1991 - 1993 Clinical Neurosurgery University of California, San Francisco


Licensure and Certification:
1981 LMCC, Medicine Medical Council of Canada
1990 Certification, Neurosurgery Province of Québec, Canada
1990 Certification, Neurosurgery Royal College of Surgeons (C)
1990 Written, Neurosurgery American Board of Neurosurgery
1991-1994 Certificate of Registration State of California
1993-present Certificate of Registration District of Columbia

Academic Appointments:
1991-1993 Visiting Assistant Professor Departments of Neurosurgery and Anatomy University of California, San Francisco
1993-2000 Assistant Professor Departments of Neurosurgery & Cell Biology, Georgetown University, Washington, DC
1998-2000 Assistant Research Anatomist University of California, San Francisco
2000-present Assistant Professor, University of California, San Francisco

Other Professional Positions and Major Visiting Appointments:
1998-2000 Assistant Research Anatomist University of California, San Francisco
1998-2000 Associate Professor Universtity of Québec, Rouyn Noranda


Awards and Honors
1990-1991 Fonds de la Recherche en Santé du Québec Fellowship,
1990-1991 McLaughlin Fellowship
1990-1991 MRC Research Fellowship
1990-1993 MRC Centennial Fellowship
1990-1996 MRC Clinician-Scientist Fellow
1993 Winter Conference on Brain Research Fellow
1994 Wellcome Trust Travel Award
1994-1995 Georgetown University New Investigator Award


Part II: Research, Teaching, and Clinical Contributions


Report of Clinical Activities

Field: Neurosurgery
Areas of major focus:
Pain - trigeminal neuralgia, glossopharyngial neuralgia, occipital neuralgia, postherpetic pain, central and phantom pain, Carpal tunnel syndrome
Abnormal movements - Parkinson’s disease, Tic Convulsif (Seventh nerve tic), Spasmodic torticollis
Epilepsy
Obsessive-Compulsive disorders
AIDS related brain disorders
Radiosurgery and Brachytherapy for brain tumors, vascular malformations
Sites of practice:
University of California San Francisco (Fellowship from 1991 to 1993)
Georgetown University Medical Center (1993 to 1997)


Part III: Bibliography


Original Articles

1. Corman J, Jasmin L, Bayardelle P, Daloze P, Smeesters C, Peloquin A, Gagnon, R, Falardeau, M. [Diagnosis and treatment of hepatic abscess at Notre Dame Hospital. Study of prognostic factors]. Union Med Can 1983; 112:1009-13.
2. Jasmin L, Courville J, Bakker DA. Afferent projections from forelimb muscles to the external and main cuneate nuclei in the cat. A study with transganglionic transport of horseradish peroxidase. Anat Embryol 1985; 171:275-84.
3. Jasmin L, Courville J. Distribution of external cuneate nucleus afferents to the cerebellum. II. Topographical distribution and zonal pattern. An experimental study with radioactive tracers in the cat. J Comp Neurol 1987; 261:497-514.
4. Jasmin L, Courville J. Distribution of external cuneate nucleus afferents to the cerebellum. I. Comparisons with projections from the main cuneate and other adjacent nuclei. An experimental study with radioactive tracers in the cat. J Comp Neurol 1987; 261:481-96.
5. Jasmin L, Gogas KR, Ahlgren SC, Levine JD, Basbaum AI. Walking evokes a distinctive pattern of Fos-like immunoreactivity in the caudal brainstem and spinal cord of the rat. Neuroscience 1994; 58:275-86.
6. Liu H, Brown JL, Jasmin L, Maggio JE, Vigna SR , Mantyh PW, Basbaum AI. Synaptic relationship between substance P and the substance P receptor: Light and electron microscopic characterization of the mismatch between neuropeptides and their receptors. Proc Natl Acad Sci USA 1994; 91:1009-13.
7. Jasmin L, Tarczy-Hornoch L, Wang H, Levine JD, and Basbaum AI. Differential effects of morphine on noxious stimulus-evoked Fos-like immunoreactivity in subpopulations of spinoparabrachial neurons. J Neurosci 1994; 14:7252-60.
8. Burkey AR, Carstens E, Wenniger JJ, Tang J, Jasmin L. An opioidergic cortical antinociception triggering site in the agranular insular cortex of the rat that contributes to morphine antinociception. J Neurosci 1996; 16:6612-23.
9. Jasmin L, Carstens E, Basbaum AI. Interneurons presynaptic to rat tail flick motoneurons as mapped by transneuronal transport of pseudorabies virus: few have long ascending collaterals. Neuroscience 1997; 76:859-76.
10. Jasmin L, Burkey AR, Card JP, Basbaum AI. Transneuronal labeling of a nociceptive pathway, the spino-(trigemino-)parabrachio-amygdaloid, in the rat. J Neurosci 1997; 17:3751-65.
11. Goff JR, Burkey AR, Goff DJ, Jasmin L. Reorganization of the spinal dorsal horn in models of chronic pain: correlation with behavior. Neuroscience 1998; 82:559-74.
12.Jasmin L, Kohan L, Franssen M, Janni G. Goff JR. The cold plate as a test of nociceptive behavior: description and application to the study of chronic neuropathic and inflammatory pain models. Pain 1998; 75:367-82.
13.Pikov V, Gillis RA, Jasmin L, Wrathall JR. Assessment of lower urinary tract functional deficit in rats with contusive spinal cord injury. J Neurotrauma 1998; 15:375-86.
14.Jasmin L, Janni G, Manz HJ, Rabkin SD. Activation of CNS circuits producing a neurogenic cystitis: evidence for centrally induced peripheral inflammation. J Neurosci 1998; 18:10016-29.
15.Doggweiler R, Jasmin L, Schmidt RA. Neurogenically mediated cystitis in rats: An animal model. J Urol 1998; 160: 1551-6.
16.Burkey AR, Carstens E, Jasmin L. Dopamine reuptake inhibition in the rostral agranular insular cortex (RAIC) produces antinociception. J Neurosci 1999; 19:4169-79
17.Jasmin L., G. Janni, P.T. Ohara, S.D. Rabkin (2000) "CNS induced neurogenic cystitis is associated with bladder mast cell degranulation in the rat" J Urol 164(3 Pt 1), 852-855
18.Jasmin L, G. Janni, T. Moallem, D.A. Lappi, P.T. Ohara (2000) "Schwann Cells Are Removed from the Spinal Cord after Effecting Recovery from Paraplegia". J Neurosci. 20, 9215-9223.
19. Miao, F. J.-P., L Jasmin, W. Jänig, P.H. Heller, R. Gear, J.D. Levine (2001) "Spino-bulbo-spinal pathway mediating vagal modulation of nociceptive-neuroendocrine control of inflammation in the rat.."J Physiol 552:811-822
20. Rambold H., A Churchland, Y Selig, L Jasmin, SG Lisberger (2001) "Partial ablation of the flocculus and ventral paraflocculus in monkeys cause linked deficit in smooth pursuit eye movement and adaptive modification of the VOR. J Neurophysiol 87: 912-924.
21.Jasmin L., D. Tien, D. Weinshenker, R.D. Palmiter, P.G. Green, G. Janni & P.T. Ohara (2002) “The NK1 receptor mediates both the hyperalgesia and the resistance to morphine in mice lacking noradrenaline” PNAS 99(2):1029-1034.
22. Jasmin, L. and Ohara, P.T. (2002) Do Schwann cells pave the way for oligodendrocytes? The Neuroscientist. vol. 8, no. 3:198-203.
23. Jasmin L., PT Ohara, and NM Barbaro (2002). Central Pain. In: Textbook of Neurological Surgery. Lippincott Williams & Wilkins, Philadelphia, vol 4, pp 3004-3013.
24. Tien, D., P.T. Ohara, A.A. Larson, L. Jasmin (2003) “Vagal afferents are necessary for the establishment but not the maintenance of kainic acid-induced hyperalgesia in mice”. Pain, 102(1-2):39-49.
25. Jasmin, L, A. Boudah, P.T. Ohara. (2003) Long-term effects of decreased noradrenergic CNS innervation on pain behavior and opioid antinociception. J Comp Neurol, 460(1):38-55.
26. Miao, F. J.-P, W. Jänig, L. Jasmin, J.D. Levine (2003). Blockade of nociceptive inhibition of plasma extravasation by opioid stimulation of the periaqueductal gray and its interaction with vagus-induced inhibition in the rat. Neuroscience 119:875-885.
27. Ohara, Peter T., Alberto Granato, Theodore M. Moallem, Bai-Ren Wang, Yves Tillet, Luc Jasmin (2003). Dopamine input to GABAergic neurons in the rostral agranular insular cortex. Journal of Neurocytology (in press).
28. Jasmin, L. and Ohara (2003) Identification of nociceptive neurons by retrograde labeling. In Pain Research. Methods in Molecular Medicine. Humana Press (in press).

29. Jasmin, L., A Boudah, P.T. Ohara (2003). Analgesia and hyperalgesia by GABAergic modulation of the cerebral cortex. Nature (in press).


Proceedings of Meetings
1. Jasmin L, Tarczy-Hornoch K, Wang H, Levine JD, Basbaum AI. Transneuronal spread of the pseudorabies virus after injection into the central nucleus of the amygdala in the rat. Gene Ther 1994; 1 Suppl 1: S74.
2. Jasmin L, Janni G. Experimental Neurogenic Cystitis. In :Bladder Disease: Research Concepts and Clinical Applications; 2000 (in press)
Reviews, Chapters, and Editorials
1. Jasmin L. Pseudorabies virus as a neuroanatomical tracer. J Neurovirol 1995; 1:326-7.
2. Jasmin L, and A. Burkey. Molecular Biology of Pain. In: Raffel C, Harsh G, editors. The Molecular biology of neurosurgical disease. Philadelphia: Williams & Wilkin; 1996. p.362-72.
3. Jasmin L. Treating Parkinsonian pain: the role of the dopaminergic system. Neurol Rev 1998; suppl April: 6.
4. Jasmin L, PT Ohara, and NM Barbaro. Central Pain. In: Texbook of Neurological Surgery. (in press)
5. Jasmin L and G Janni. "Experimental Neurogenic Cystitis" In: Bladder Disease: Research Concepts and Clinical Applications (in press).


Educational Material
1. Jasmin L (Chair), Mason P, Stein C. Peripheral and Central Sites of Opiate Antinociception. Professional Development Course. Washington, DC: American Pain Society 15th Annual Scientific Meeting; 1996.
2. Jasmin L (Chair), King S, Chudler E. Parkinsonian Pain. Professional Development Course. New Orleans: American Pain Society 16th Annual Scientific Meeting; 1997.
3. Jasmin, L (Chair), LA. Bradley, D. Claw, R.H. Gracely, and S. Marchand. "Fibromyalgia: A CNS Disease. Professional Development Course. Fort Lauderdale: American Pain Society 18th Annual Scientific Meeting; 1999.
4. Jasmin, L (Chair), JP Nguyen, D. Bowsher, F. Lenz. "Central Pain". Symposium. Atlanta: American Pain Society 19th Annual Scientific Meeting; 2000.


Thesis
Jasmin L. Topographical distribution of afferents and efferents of the external cuneate nucleus in the cat [thesis]. Montréal (QC): Univer. Montréal; 1987.


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